Top Guidelines Of phenobarbital sodium tablets
Top Guidelines Of phenobarbital sodium tablets
Blog Article
Contraindicated (1)pentobarbital will minimize the level or effect of lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Coadministration with strong CYP3A4 inducers can lead to diminished serum concentrations and loss of antimalarial efficacy
pentobarbital will decrease the level or effect of vinorelbine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Small/Significance Unfamiliar.
pentobarbital will reduce the level or effect of darifenacin by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will reduce the extent or effect of bazedoxifene/conjugated estrogens by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
Phenytoin, sodium valproate, valproic acid: The effect of barbiturates to the metabolism of phenytoin seems to generally be variable. Some investigators report an accelerating effect, whilst others report no effect. Because the effect of barbiturates on the metabolism of phenytoin just isn't predictable, phenytoin and barbiturate blood stages really should be monitored extra commonly if these drugs are supplied concurrently.
pentobarbital improves toxicity of ifosfamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. CYP3A4 inducers may well improve the metabolism of ifosfamide to its active alkylating metabolites.
pentobarbital will lessen the extent or effect of alosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance get more info Unfamiliar.
pentobarbital will reduce the extent or effect of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Sturdy CYP3A4 inducers might minimize suvorexant efficacy; if enhanced suvorexant dose required, usually do not exceed twenty mg/working day
pentobarbital will minimize the extent or effect of amiodarone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
pentobarbital decreases amounts of amphotericin B deoxycholate by inhibition of GI absorption. Applies only to oral sort of equally agents. Slight/Significance Unidentified.
pentobarbital will minimize the level or effect of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
Contraindicated (1)pentobarbital will lessen the extent or effect of elbasvir/grazoprevir by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
TIME may obtain compensation for some inbound links to services on this Web site. Presents may be topic to change without discover.
pentobarbital will reduce the level or effect of cilostazol by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.